Sildenafil (a phosphodiesterase-5 inhibitor) is used to restore the erectile dysfunction (ED). Its chemical structure is somewhat similar to cyclic guanosine monophosphate molecule and according to the trials, the onset of its active functions range from 20 minutes to 18 hours depending on the body metabolism. The discovery of sildenafil citrate was initiated by Dr Furchgott, Ignarro and Murad. They have established a nexus between nitric oxide (NO) and cardiovascular system of humans. Nitric oxide acts as a neurotransmitter that goads the nutrients blood vessels of the heart, thereby increasing the flow.

Over the years there has been only one question regarding this medicine and that is revolving around sildenafil citrate OTC. It simply means whether it should be allowed over the counter (OTC) or not.

Reasons in favour:-

• There has been a paradigm shift in the health care system, form visiting clinics to self-medication on the consultation of doctors. This has empowered people to govern their health care decision and manages their illness.

 Challenges for sildenafil citrate OTC:-

• There is a need to develop a proper connection between the medicine holders (pharmaceutical firms, drug regulatory agencies) and various health’s funding institution (National Health Service and insurance companies).

• Various pharmacists faced problem in identifying customers less than 16 years of age.

 What can be done:-

• According to the study published by one the eminent medical bulletin, sildenafil citrate OTC can be done However few screening and risks associated with this should be conveyed to the persons before they take it home.

 Erectile dysfunction (ED) was not considered as a life-threatening situation by various governments however sildenafil citrate was given a licensed for the treatment of ED. The prime controversy surrounding the sildenafil citrate is that it is being used as a lifestyle drug. Lifestyle drug means medicines that are used to consummate non-health related issues. This drug allures the mostly men between aged 18 and 45 years, which is causing one concern that if they started not using the drug after some time, they may face a problem.

 Well, this article covers various aspects related to the so-called lifestyle drug, till now you have learned about its molecule, its functions, and then issues surrounding the sildenafil citrate OTC. According to the recommendation of the doctors, if there is a minor problem of ED, then traditional medicine should be used initially and sildenafil citrate is to be saved for a later stage if the problem persists.